Your actions now determine your future

Study Title
Intake of niacin, folate, vitamin B-6, and vitamin B-12 through young adulthood and cognitive function in midlife: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Study Authors Bo Qin, Pengcheng Xun, David R Jacobs, Jr., Na Zhu, Martha L Daviglus, Jared P Reis, Lyn M Steffen, Linda Van Horn, Stephen Sidney, Ka He
Study Model Human
Abstract Link


Here we go again, I’m trying to play with the format of these articles to keep them short and sweet (so that we don’t get bored). I guess it’s my ‘get to the point’ nature, which hopefully will work for you! It’s a beautiful day in London (heat wave and some rain) and I’ve just passed my kickboxing grading, which means I’m in pain, so this format change could be quite good actually. Let’s see.


Five key points from the article: 

  • Lifestyle and diet have an impact on cognitive impairment and dementia
  • B vitamins are linked to homocysteine metabolism
  • High homocysteine levels may be associated with higher risk of dementia, amyloid neurotoxicity and brain atrophy (so intake of B vitamins could be beneficial to reduce homocysteine levels)
  • Study analysed cognitive test data from over 3,000 participants after 25 years (with nutritional questionnaire data collected at 0, 7 and 20 years)
  • B vitamins could be seen as an early preventive measure with their intake in young adulthood associated with better cognitive performance in midlife


Based on the data I think it could be worth supplementing your diet with B vitamins, especially if you don’t pay attention to what you eat from a nutritional point of view (as most people I think, myself included).

There are 8 B vitamins, meat being the key dietary source of them. The crazy part is that B vitamins are present in whole unprocessed carbohydrate foods, which is lost as we process them e.g. to white flour and many countries have laws stating that B vitamins have to be added back in after processing. How crazy is that?

Dr Bart Alright


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