L-Tyrosine studies datasheet - 2019 Update

Here is a summary list of L-Tyrosine studies showing its effect on human performance.

 

Last updated: 14 May 2019 

 

Human studies  

 

Mood/Stress

 

  • Tyrosine (100mg/kg) significantly decreased symptoms, adverse moods, and performance impairments in subjects who exhibited average or greater responses to 4.5 hour exposure to cold and hypoxia conditions (Study)

  • A tyrosine supplementation review article concluded that tyrosine supplementation seems to replete neurotransmitter levels in the brain and reverse the stress-induced degradation of a variety of cognitive functions in healthy adults (Study)

 

Cognitive Performance

 

  • Limited number of studies concluded that L-Tyrosine promotes convergent ("deep") thinking (Study), cognitive flexibility (Study), and working memory (Study)

  • One study stated that tyrosine may sustain working memory when competing requirements to perform other tasks simultaneously degrade performance, and that supplemental tyrosine may be appropriate for maintaining performance when mild to severe decrements are anticipated (Study)

 

 

Animal studies 

 

  • A depression study in rats observed that L-tyrosine-loaded nanoparticles (10 mg/kg) significantly decreased the immobility time in the FST, concomitant with restoration of the basal levels of locomotor activity, distance travelled and rearing counts. Positive results, through behavioural tests, are probably attributed to restoring the basal levels of the cerebral noradrenaline (Study

  • It appears that tyrosine supplementation was effective in reducing effects of stress in the aged animals challenged with cold swim, possibly by virtue of its relationship to catecholamine metabolism (Study

  • A study stated that brain tyrosine level can affect the rates at which catecholaminergic neurons synthesize and turn over their transmitters and that tyrosine administration to rats causes proportional increases in brain tyrosine levels and in the accumulation of the norepinephrine metabolite (Study)
     
  • Another study found that animals receiving tyrosine-enriched diet displayed neither the stress-induced depletion of norepinephrine nor the behavioral depression. Authors concluded that supplementary tyrosine may be useful therapeutically in people exposed chronically to stress (Study)

 

 

L-Tyrosine food sources 

 

  • Cheese
  • Soybeans 
  • Beef 
  • Lamb
  • Pork
  • Fish and seafood
  • Chicken
  • Turkey
  • Eggs
  • Dairy
  • Pumpkin seeds 
  • Wholegrains
  • Beans and lentils 

 

 

For more information about food sources visit https://ndb.nal.usda.gov/ndb/

For more Niacin studies visit https://www.ncbi.nlm.nih.gov/pubmed/?term=l-tyrosine 

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